Restoration of Vision with Ectopic Expression of Human Rod Opsin

Many retinal dystrophies result in photoreceptor loss, but the inner retinal neurons can survive, making them potentially amenable to emerging optogenetic therapies. Here, we show that ectopically expressed human rod opsin, driven by either a non-selective or ON-bipolar cell-specific promoter, can f...

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Dades bibliogràfiques
Publicat a:Curr Biol
Autors principals: Cehajic-Kapetanovic, Jasmina, Eleftheriou, Cyril, Allen, Annette E., Milosavljevic, Nina, Pienaar, Abigail, Bedford, Robert, Davis, Katherine E., Bishop, Paul N., Lucas, Robert J.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540256/
https://ncbi.nlm.nih.gov/pubmed/26234216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.07.029
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