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Efficacy and Safety of Glycosidic Enzymes for Improved Gene Delivery to the Retina following Intravitreal Injection in Mice

Viral gene delivery is showing great promise for treating retinal disease. Although subretinal vector delivery has mainly been used to date, intravitreal delivery has potential advantages if low retinal transduction efficiency can be overcome. To this end, we investigated the effects of co-injection...

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Publicado en:Mol Ther Methods Clin Dev
Autores principales: Cehajic-Kapetanovic, Jasmina, Milosavljevic, Nina, Bedford, Robert A., Lucas, Robert J., Bishop, Paul N.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948313/
https://ncbi.nlm.nih.gov/pubmed/29766027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.12.002
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