Restoration of Vision with Ectopic Expression of Human Rod Opsin

Many retinal dystrophies result in photoreceptor loss, but the inner retinal neurons can survive, making them potentially amenable to emerging optogenetic therapies. Here, we show that ectopically expressed human rod opsin, driven by either a non-selective or ON-bipolar cell-specific promoter, can f...

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Publicado en:Curr Biol
Main Authors: Cehajic-Kapetanovic, Jasmina, Eleftheriou, Cyril, Allen, Annette E., Milosavljevic, Nina, Pienaar, Abigail, Bedford, Robert, Davis, Katherine E., Bishop, Paul N., Lucas, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540256/
https://ncbi.nlm.nih.gov/pubmed/26234216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.07.029
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