α-Catenin–mediated cadherin clustering couples cadherin and actin dynamics

The function of the actin-binding domain of α-catenin, αABD, including its possible role in the direct anchorage of the cadherin–catenin complex to the actin cytoskeleton, has remained uncertain. We identified two point mutations on the αABD surface that interfere with αABD binding to actin and used...

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Gepubliceerd in:J Cell Biol
Hoofdauteurs: Chen, Chi-Shuo, Hong, Soonjin, Indra, Indrajyoti, Sergeeva, Alina P., Troyanovsky, Regina B., Shapiro, Lawrence, Honig, Barry, Troyanovsky, Sergey M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2015
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539995/
https://ncbi.nlm.nih.gov/pubmed/26261181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412064
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