α-Catenin–mediated cadherin clustering couples cadherin and actin dynamics

The function of the actin-binding domain of α-catenin, αABD, including its possible role in the direct anchorage of the cadherin–catenin complex to the actin cytoskeleton, has remained uncertain. We identified two point mutations on the αABD surface that interfere with αABD binding to actin and used...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Chen, Chi-Shuo, Hong, Soonjin, Indra, Indrajyoti, Sergeeva, Alina P., Troyanovsky, Regina B., Shapiro, Lawrence, Honig, Barry, Troyanovsky, Sergey M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539995/
https://ncbi.nlm.nih.gov/pubmed/26261181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412064
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