α-Catenin–mediated cadherin clustering couples cadherin and actin dynamics

The function of the actin-binding domain of α-catenin, αABD, including its possible role in the direct anchorage of the cadherin–catenin complex to the actin cytoskeleton, has remained uncertain. We identified two point mutations on the αABD surface that interfere with αABD binding to actin and used...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Chen, Chi-Shuo, Hong, Soonjin, Indra, Indrajyoti, Sergeeva, Alina P., Troyanovsky, Regina B., Shapiro, Lawrence, Honig, Barry, Troyanovsky, Sergey M.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539995/
https://ncbi.nlm.nih.gov/pubmed/26261181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412064
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