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α-Catenin–mediated cadherin clustering couples cadherin and actin dynamics

The function of the actin-binding domain of α-catenin, αABD, including its possible role in the direct anchorage of the cadherin–catenin complex to the actin cytoskeleton, has remained uncertain. We identified two point mutations on the αABD surface that interfere with αABD binding to actin and used...

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Dettagli Bibliografici
Pubblicato in:J Cell Biol
Autori principali: Chen, Chi-Shuo, Hong, Soonjin, Indra, Indrajyoti, Sergeeva, Alina P., Troyanovsky, Regina B., Shapiro, Lawrence, Honig, Barry, Troyanovsky, Sergey M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539995/
https://ncbi.nlm.nih.gov/pubmed/26261181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412064
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