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Identification of in vitro and in vivo disconnects using transcriptomic data

BACKGROUND: Integrating transcriptomic experiments within drug development is increasingly advocated for the early detection of toxicity. This is partly to reduce costs related to drug failures in the late, and expensive phases of clinical trials. Such an approach has proven useful both in the study...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Otava, Martin, Shkedy, Ziv, Talloen, Willem, Verheyen, Geert R, Kasim, Adetayo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539666/
https://ncbi.nlm.nih.gov/pubmed/26282683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1726-7
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