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Identification of in vitro and in vivo disconnects using transcriptomic data

BACKGROUND: Integrating transcriptomic experiments within drug development is increasingly advocated for the early detection of toxicity. This is partly to reduce costs related to drug failures in the late, and expensive phases of clinical trials. Such an approach has proven useful both in the study...

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Bibliografski detalji
Izdano u:BMC Genomics
Glavni autori: Otava, Martin, Shkedy, Ziv, Talloen, Willem, Verheyen, Geert R, Kasim, Adetayo
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539666/
https://ncbi.nlm.nih.gov/pubmed/26282683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1726-7
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