A random effects model for the identification of differential splicing (REIDS) using exon and HTA arrays

BACKGROUND: Alternative gene splicing is a common phenomenon in which a single gene gives rise to multiple transcript isoforms. The process is strictly guided and involves a multitude of proteins and regulatory complexes. Unfortunately, aberrant splicing events do occur which have been linked to gen...

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Détails bibliographiques
Publié dans:BMC Bioinformatics
Auteurs principaux: Van Moerbeke, Marijke, Kasim, Adetayo, Talloen, Willem, Reumers, Joke, Göhlmann, Hinrick W. H., Shkedy, Ziv
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Methodology Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445373/
https://ncbi.nlm.nih.gov/pubmed/28545391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1687-8
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