Cross talk between the bombesin neuropeptide receptor and Sonic hedgehog pathways in small cell lung carcinoma

Small cell lung carcinoma (SCLC) often features the up-regulation of the Sonic Hedgehog (Shh) pathway leading to activation of Gli transcription factors. SCLC cells secrete bombesin (BBS)-like neuropeptides (BLPs) that act as autocrine growth factors. Here, we show that SCLC tumour samples feature c...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncogene
Autori principali: Castellone, Maria Domenica, Laukkanen, Mikko O., Teramoto, Hidemi, Bellelli, Roberto, Alì, Greta, Fontanini, Gabriella, Santoro, Massimo, Gutkind, J Silvio
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539617/
https://ncbi.nlm.nih.gov/pubmed/24747971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.104
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi