CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa

The long-term outcome of neuroprotection as a therapeutic strategy for preventing cell death in neurodegenerative disorders remains unknown, primarily due to slow disease progression and the inherent difficulty of assessing neuronal survival in vivo. Employing a murine model of retinal disease, we d...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Lipinski, Daniel M, Barnard, Alun R, Singh, Mandeep S, Martin, Chris, Lee, Edward J, Davies, Wayne I L, MacLaren, Robert E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539573/
https://ncbi.nlm.nih.gov/pubmed/25896245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.68
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