Characterization of a Dominant Cone Degeneration in a Green Fluorescent Protein–Reporter Mouse with Disruption of Loci Associated with Human Dominant Retinal Dystrophy

PURPOSE. To characterize anatomically and functionally the retinal degeneration observed in a transgenic mouse line (OPN1LW-EGFP) expressing enhanced green fluorescent protein (EGFP) in a subpopulation of cone photoreceptors, and to map the location of the transgenic insertion. METHODS. An anatomic...

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Main Authors: Lipinski, Daniel M., Yusuf, Mohammed, Barnard, Alun R., Damant, Christopher, Issa, Peter Charbel, Singh, Mandeep S., Lee, Edward, Davies, Wayne L., Volpi, Emanuela V., MacLaren, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175985/
https://ncbi.nlm.nih.gov/pubmed/21705682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7932
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