CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa

The long-term outcome of neuroprotection as a therapeutic strategy for preventing cell death in neurodegenerative disorders remains unknown, primarily due to slow disease progression and the inherent difficulty of assessing neuronal survival in vivo. Employing a murine model of retinal disease, we d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Ther
Prif Awduron: Lipinski, Daniel M, Barnard, Alun R, Singh, Mandeep S, Martin, Chris, Lee, Edward J, Davies, Wayne I L, MacLaren, Robert E
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539573/
https://ncbi.nlm.nih.gov/pubmed/25896245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.68
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