Sleeping Beauty Transposon-mediated Engineering of Human Primary T Cells for Therapy of CD19(+) Lymphoid Malignancies

We have reported earlier that the non-viral Sleeping Beauty (SB) transposon system can mediate genomic integration and long-term reporter gene expression in human primary peripheral blood (PB) T cells. In order to test whether this system can be used for genetically modifying both PB T cells and umb...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Huang, Xin, Guo, Hongfeng, Kang, Johnthomas, Choi, Suet, Zhou, Tom C, Tammana, Syam, Lees, Christopher J, Li, Zhong-Ze, Milone, Michael, Levine, Bruce L, Tolar, Jakub, June, Carl H, Mclvor, R Scott, Wagner, John E, Blazar, Bruce R, Zhou, Xianzheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539139/
https://ncbi.nlm.nih.gov/pubmed/18227839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mt.6300404
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