4-1BB and CD28 Signaling Plays a Synergistic Role in Redirecting Umbilical Cord Blood T Cells Against B-Cell Malignancies

Umbilical cord blood (UCB) T cells can be redirected to kill leukemia and lymphoma cells by engineering with a single-chain chimeric antigen receptor (CAR) and thus may have general applications in adoptive cell therapy. However, the role of costimulatory molecules in UCB T-cell activation and effec...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Tammana, Syam, Huang, Xin, Wong, Marianna, Milone, Michael C., Ma, Linan, Levine, Bruce L., June, Carl H., Wagner, John E., Blazar, Bruce R., Zhou, Xianzheng
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2010
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861957/
https://ncbi.nlm.nih.gov/pubmed/19719389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.122
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares