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The Biology of Proteostasis in Aging and Disease
Loss of protein homeostasis (proteostasis) is a common feature of aging and disease that is characterized by the appearance of nonnative protein aggregates in various tissues. Protein aggregation is routinely suppressed by the proteostasis network (PN), a collection of macromolecular machines that o...
Gorde:
| Argitaratua izan da: | Annu Rev Biochem |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539002/ https://ncbi.nlm.nih.gov/pubmed/25784053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-060614-033955 |
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