Hepatic Stellate Cells Orchestrate Clearance of Necrotic Cells in a HIF-1α-dependent Manner by Modulating Macrophage Phenotype in Mice

Hypoxia-inducible factor-1α (HIF-1α) is activated in hepatic stellate cells (HSCs) by hypoxia, and regulates genes important for tissue repair. Whether HIF-1α is activated in HSCs after acute injury and contributes to liver regeneration, however, is not known. To investigate this, mice were generate...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Mochizuki, Akie, Pace, Aaron, Rockwell, Cheryl E., Roth, Katherine J., Chow, Aaron, O'Brien, Kate M, Albee, Ryan, Kelly, Kara, Towery, Keara, Luyendyk, James P., Copple, Bryan L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538924/
https://ncbi.nlm.nih.gov/pubmed/24639359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303195
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