Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation

During ribosomal translation, the two ribosomal subunits remain associated through intersubunit bridges, despite rapid large-scale intersubunit rotation. The absence of large barriers hindering rotation is a prerequisite for rapid rotation. Here, we investigate how such a flat free-energy landscape...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Bock, Lars V., Blau, Christian, Vaiana, Andrea C., Grubmüller, Helmut
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538834/
https://ncbi.nlm.nih.gov/pubmed/26109353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv649
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