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Synthesis of 2′-Fluoro RNA by Syn5 RNA polymerase
The substitution of 2′-fluoro for 2′-hydroxyl moieties in RNA substantially improves the stability of RNA. RNA stability is a major issue in RNA research and applications involving RNA. We report that the RNA polymerase from the marine cyanophage Syn5 has an intrinsic low discrimination against the...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538805/ https://ncbi.nlm.nih.gov/pubmed/25897116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv367 |
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