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Single-cell, locus-specific bisulfite sequencing (SLBS) for direct detection of epimutations in DNA methylation patterns

Stochastic epigenetic changes drive biological processes, such as development, aging and disease. Yet, epigenetic information is typically collected from millions of cells, thereby precluding a more precise understanding of cell-to-cell variability and the pathogenic history of epimutations. Here we...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Gravina, Silvia, Ganapathi, Shireen, Vijg, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538804/
https://ncbi.nlm.nih.gov/pubmed/25897117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv366
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