Plasmodium Infection Promotes Genomic Instability and AID Dependent B Cell Lymphoma

Chronic infection with Plasmodium falciparum was epidemiologically associated with endemic Burkitt’s lymphoma, a mature B cell cancer characterized by chromosome translocation between the c-myc oncogene and Igh, over 50 years ago. Whether infection promotes B cell lymphoma, and if so by what mechani...

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Udgivet i:Cell
Main Authors: Robbiani, Davide F., Deroubaix, Stephanie, Feldhahn, Niklas, Oliveira, Thiago Y., Callen, Elsa, Wang, Qiao, Jankovic, Mila, Silva, Israel T., Rommel, Philipp C., Bosque, David, Eisenreich, Tom, Nussenzweig, André, Nussenzweig, Michel C.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538708/
https://ncbi.nlm.nih.gov/pubmed/26276629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.07.019
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