Plasmodium Infection Promotes Genomic Instability and AID Dependent B Cell Lymphoma

Chronic infection with Plasmodium falciparum was epidemiologically associated with endemic Burkitt’s lymphoma, a mature B cell cancer characterized by chromosome translocation between the c-myc oncogene and Igh, over 50 years ago. Whether infection promotes B cell lymphoma, and if so by what mechani...

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Pubblicato in:Cell
Autori principali: Robbiani, Davide F., Deroubaix, Stephanie, Feldhahn, Niklas, Oliveira, Thiago Y., Callen, Elsa, Wang, Qiao, Jankovic, Mila, Silva, Israel T., Rommel, Philipp C., Bosque, David, Eisenreich, Tom, Nussenzweig, André, Nussenzweig, Michel C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538708/
https://ncbi.nlm.nih.gov/pubmed/26276629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.07.019
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