The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo

Human single-stranded DNA-binding protein 1 (hSSB1), encoded by OBFC2B, was recently characterized as an essential factor for the initiation of DNA damage checkpoints and the maintenance of genomic stability. Here, we report that loss of Obfc2b in mice results in perinatal lethality characterized by...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Feldhahn, Niklas, Ferretti, Elisabetta, Robbiani, Davide F, Callen, Elsa, Deroubaix, Stephanie, Selleri, Licia, Nussenzweig, Andre, Nussenzweig, Michel C
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474923/
https://ncbi.nlm.nih.gov/pubmed/22940690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.247
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker