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Gating of a mechanosensitive channel due to cellular flows

A multiscale continuum model is constructed for a mechanosensitive (MS) channel gated by tension in a lipid bilayer membrane under stresses due to fluid flows. We illustrate that for typical physiological conditions vesicle hydrodynamics driven by a fluid flow may render the membrane tension suffici...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pak, On Shun, Young, Y.-N., Marple, Gary R., Veerapaneni, Shravan, Stone, Howard A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538622/
https://ncbi.nlm.nih.gov/pubmed/26216988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512152112
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