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Analytic models for mechanotransduction: Gating a mechanosensitive channel

Analytic estimates for the forces and free energy generated by bilayer deformation reveal a compelling and intuitive model for MscL channel gating analogous to the nucleation of a second phase. We argue that the competition between hydrophobic mismatch and tension results in a surprisingly rich stor...

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Autors principals: Wiggins, Paul, Phillips, Rob
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC384697/
https://ncbi.nlm.nih.gov/pubmed/15024097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307804101
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