One face of a transmembrane helix is crucial in mechanosensitive channel gating
MscL is a mechanosensitive channel in bacteria that responds directly to membrane tension by opening a large conductance pore. To determine functionally important residues within this molecule, we have randomly mutagenized mscL, expressed the genes in living bacteria, and screened for gain-of-functi...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736761/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.19.11471 |
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