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The mechanosensitive Piezo1 channel is required for bone formation

Mechanical load of the skeleton system is essential for the development, growth, and maintenance of bone. However, the molecular mechanism by which mechanical stimuli are converted into osteogenesis and bone formation remains unclear. Here we report that Piezo1, a bona fide mechanotransducer that is...

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Detalhes bibliográficos
Principais autores: Weijia Sun, Shaopeng Chi, Yuheng Li, Shukuan Ling, Yingjun Tan, Youjia Xu, Fan Jiang, Jianwei Li, Caizhi Liu, Guohui Zhong, Dengchao Cao, Xiaoyan Jin, Dingsheng Zhao, Xingcheng Gao, Zizhong Liu, Bailong Xiao, Yingxian Li
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2019-07-01
coleção:eLife
Assuntos:
Acesso em linha:https://elifesciences.org/articles/47454
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