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Analytic models for mechanotransduction: Gating a mechanosensitive channel
Analytic estimates for the forces and free energy generated by bilayer deformation reveal a compelling and intuitive model for MscL channel gating analogous to the nucleation of a second phase. We argue that the competition between hydrophobic mismatch and tension results in a surprisingly rich stor...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC384697/ https://ncbi.nlm.nih.gov/pubmed/15024097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307804101 |
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