Influenza A(H7N9) Virus Acquires Resistance-Related Neuraminidase I222T Substitution When Infected Mallards Are Exposed to Low Levels of Oseltamivir in Water

Influenza A virus (IAV) has its natural reservoir in wild waterfowl, and new human IAVs often contain gene segments originating from avian IAVs. Treatment options for severe human influenza are principally restricted to neuraminidase inhibitors (NAIs), among which oseltamivir is stockpiled in prepar...

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發表在:Antimicrob Agents Chemother
Main Authors: Gillman, Anna, Nykvist, Marie, Muradrasoli, Shaman, Söderström, Hanna, Wille, Michelle, Daggfeldt, Annika, Bröjer, Caroline, Waldenström, Jonas, Olsen, Björn, Järhult, Josef D.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
主題:
Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538561/
https://ncbi.nlm.nih.gov/pubmed/26077257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00886-15
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