Oseltamivir-Resistant Influenza A (H1N1) Virus Strain with an H274Y Mutation in Neuraminidase Persists without Drug Pressure in Infected Mallards

Influenza A virus (IAV) has its natural reservoir in wild waterfowl, and emerging human IAVs often contain gene segments from avian viruses. The active drug metabolite of oseltamivir (oseltamivir carboxylate [OC]), stockpiled as Tamiflu for influenza pandemic preparedness, is not removed by conventi...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Gillman, Anna, Muradrasoli, Shaman, Söderström, Hanna, Holmberg, Fredrik, Latorre-Margalef, Neus, Tolf, Conny, Waldenström, Jonas, Gunnarsson, Gunnar, Olsen, Björn, Järhult, Josef D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Public and Environmental Health Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357928/
https://ncbi.nlm.nih.gov/pubmed/25616792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.04034-14
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