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Environmental Levels of the Antiviral Oseltamivir Induce Development of Resistance Mutation H274Y in Influenza A/H1N1 Virus in Mallards

Oseltamivir (Tamiflu®) is the most widely used drug against influenza infections and is extensively stockpiled worldwide as part of pandemic preparedness plans. However, resistance is a growing problem and in 2008–2009, seasonal human influenza A/H1N1 virus strains in most parts of the world carried...

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Autors principals: Järhult, Josef D., Muradrasoli, Shaman, Wahlgren, John, Söderström, Hanna, Orozovic, Goran, Gunnarsson, Gunnar, Bröjer, Caroline, Latorre-Margalef, Neus, Fick, Jerker, Grabic, Roman, Lennerstrand, Johan, Waldenström, Jonas, Lundkvist, Åke, Olsen, Björn
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171471/
https://ncbi.nlm.nih.gov/pubmed/21931841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024742
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