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Efficacy of the Clinical Agent VT-1161 against Fluconazole-Sensitive and -Resistant Candida albicans in a Murine Model of Vaginal Candidiasis
Vulvovaginal candidiasis (VVC) and recurrent VVC (RVVC) remain major health problems for women. VT-1161, a novel fungal CYP51 inhibitor which has potent antifungal activity against fluconazole-sensitive Candida albicans, retained its in vitro potency (MIC(50) of ≤0.015 and MIC(90) of 0.12 μg/ml) aga...
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| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538529/ https://ncbi.nlm.nih.gov/pubmed/26124165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00185-15 |
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