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In Vitro Study of the Variable Effects of Proton Pump Inhibitors on Voriconazole

Voriconazole is a broad-spectrum antifungal agent used for the treatment of severe fungal infections. Maintaining therapeutic concentrations of 1 to 5.5 μg/ml is currently recommended to maximize the exposure-response relationship of voriconazole. However, this is challenging, given the highly varia...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Niece, Krista L., Boyd, Natalie K., Akers, Kevin S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538514/
https://ncbi.nlm.nih.gov/pubmed/26124167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00884-15
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