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Systematic Review of Mutations in Pyrazinamidase Associated with Pyrazinamide Resistance in Mycobacterium tuberculosis Clinical Isolates

Pyrazinamide (PZA) is an important first-line drug in the treatment of tuberculosis (TB) and of significant interest to the HIV-infected community due to the prevalence of TB-HIV coinfection in some regions of the world. The mechanism of resistance to PZA is unlike that of any other anti-TB drug. Th...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Ramirez-Busby, Sarah M., Valafar, Faramarz
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538510/
https://ncbi.nlm.nih.gov/pubmed/26077261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00204-15
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