The Ribosomal S10 Protein Is a General Target for Decreased Tigecycline Susceptibility

Tigecycline is a translational inhibitor with efficacy against a wide range of pathogens. Using experimental evolution, we adapted Acinetobacter baumannii, Enterococcus faecium, Escherichia coli, and Staphylococcus aureus to growth in elevated tigecycline concentrations. At the end of adaptation, 35...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Beabout, Kathryn, Hammerstrom, Troy G., Perez, Anisha Maria, Magalhães, Bárbara Freitas, Prater, Amy G., Clements, Thomas P., Arias, Cesar A., Saxer, Gerda, Shamoo, Yousif
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Mechanisms of Resistance
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538488/
https://ncbi.nlm.nih.gov/pubmed/26124155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00547-15
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