The Ribosomal S10 Protein Is a General Target for Decreased Tigecycline Susceptibility

Tigecycline is a translational inhibitor with efficacy against a wide range of pathogens. Using experimental evolution, we adapted Acinetobacter baumannii, Enterococcus faecium, Escherichia coli, and Staphylococcus aureus to growth in elevated tigecycline concentrations. At the end of adaptation, 35...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Beabout, Kathryn, Hammerstrom, Troy G., Perez, Anisha Maria, Magalhães, Bárbara Freitas, Prater, Amy G., Clements, Thomas P., Arias, Cesar A., Saxer, Gerda, Shamoo, Yousif
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2015
Pynciau:
Mechanisms of Resistance
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538488/
https://ncbi.nlm.nih.gov/pubmed/26124155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00547-15
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