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Virtual Screening and Biological Validation of Novel Influenza Virus PA Endonuclease Inhibitors
[Image: see text] The influenza virus RNA-dependent RNA polymerase complex (RdRp), a heterotrimeric protein complex responsible for viral RNA transcription and replication, represents a primary target for antiviral drug development. One particularly attractive approach is interference with the endon...
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Publicado no: | ACS Med Chem Lett |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Chemical
Society
2015
|
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538433/ https://ncbi.nlm.nih.gov/pubmed/26288686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00109 |
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