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BKCa channel activation increases cardiac contractile recovery following hypothermic ischemia/reperfusion

Mitochondrial Ca(2+)-activated large-conductance K(+) (BKCa) channels are thought to provide protection during ischemic insults in the heart. Rottlerin (mallotoxin) has been implicated as a potent BKCa activator. The purpose of this study was twofold: 1) to investigate the efficacy of BKCa channel a...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Cordeiro, Brenda, Terentyev, Dmitry, Clements, Richard T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537936/
https://ncbi.nlm.nih.gov/pubmed/26071546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00818.2014
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