Ablative Tumor Radiation Can Change the Tumor Immune Cell Microenvironment to Induce Durable Complete Remissions

PURPOSE: The goals of the study were to elucidate the immune mechanisms that contribute to desirable complete remissions of murine colon tumors treated with single radiation dose of 30 Gy. This dose is at the upper end of the ablative range used clinically to treat advanced or metastatic colorectal,...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Filatenkov, Alexander, Baker, Jeanette, Mueller, Antonia M.S., Kenkel, Justin, Ahn, G-One, Dutt, Suparna, Zhang, Nigel, Kohrt, Holbrook, Jensen, Kent, Dejbakhsh-Jones, Sussan, Shizuru, Judith A., Negrin, Robert N., Engleman, Edgar G., Strober, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537844/
https://ncbi.nlm.nih.gov/pubmed/25869387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2824
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