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Disruption of evasive immune cell microenvironment in tumors reflects immunity induced by radiation therapy

Radiation administered to murine colon tumors induced durable remissions that were dependent on CD4(+) and CD8(+) T cell immunity, and antigen cross priming CD8(+) dendritic cells (DCs). Remissions were associated with marked reductions in the infiltration of myeloid-derived suppressor cells (MDSCs)...

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Podrobná bibliografie
Vydáno v:Oncoimmunology
Hlavní autoři: Filatenkov, Alexander, Baker, Jeanette, Strober, Samuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801442/
https://ncbi.nlm.nih.gov/pubmed/27057471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1072673
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