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NKT cells act through third party bone marrow-derived cells to suppress NK cell activity in the liver and exacerbate hepatic melanoma metastases

Uveal melanoma (UM) is the most common intraocular tumor in adults and liver metastasis is the leading cause of death in UM patients. We have previously shown that NKT cell-deficient mice develop significantly fewer liver metastases from intraocular melanomas than do wild-type (WT) mice. Here, we ex...

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Detalles Bibliográficos
Publicado en:Int J Cancer
Main Authors: Sadegh, Leila, Chen, Peter W., Brown, Joseph R., Han, Zhiqiang, Niederkorn, Jerry Y.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537411/
https://ncbi.nlm.nih.gov/pubmed/25683463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29480
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