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Defective FasL expression is associated with increased resistance to melanoma liver metastases and enhanced natural kill cell activity.

OBJECTIVE: The objective was to determine if the absence of FasL signaling would affect melanoma liver metastases by influencing the anti-melanoma properties of liver natural killer (NK) cells. METHODS: Melanoma liver metastases were induced in wild-type C57BL/6 mice and the gld/gld mutant C57BL/6 m...

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Detalhes bibliográficos
Publicado no:Melanoma Res
Main Authors: Neelam, Sudha, Mellon, Jessamee, Wilkerson, Amber, Niederkorn, Jerry Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597306/
https://ncbi.nlm.nih.gov/pubmed/30932943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000614
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