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NKT cells act through third party bone marrow-derived cells to suppress NK cell activity in the liver and exacerbate hepatic melanoma metastases

Uveal melanoma (UM) is the most common intraocular tumor in adults and liver metastasis is the leading cause of death in UM patients. We have previously shown that NKT cell-deficient mice develop significantly fewer liver metastases from intraocular melanomas than do wild-type (WT) mice. Here, we ex...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Sadegh, Leila, Chen, Peter W., Brown, Joseph R., Han, Zhiqiang, Niederkorn, Jerry Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537411/
https://ncbi.nlm.nih.gov/pubmed/25683463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29480
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