The PRE-Derived NMR Model of the 38.8 kDa Tri-Domain IsdH Protein from Staphylococcus aureus Suggests that it Adaptively Recognizes Human Hemoglobin

Staphylococcus aureus is a medically important bacterial pathogen that during infections acquires iron from human hemoglobin (Hb). It uses two closely related iron regulated surface determinant (Isd) proteins to capture and extract the oxidized form of heme (hemin) from Hb, IsdH and IsdB. Both recep...

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Bibliographic Details
Published in:J Mol Biol
Main Authors: Sjodt, Megan, Macdonald, Ramsay, Spirig, Thomas, Chan, Albert H., Dickson, Claire F., Fabian, Marian, Olson, John S., Gell, David A., Clubb, Robert T.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537403/
https://ncbi.nlm.nih.gov/pubmed/25687963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.02.008
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