The Staphylococcus aureus Protein IsdH Inhibits Host Hemoglobin Scavenging to Promote Heme Acquisition by the Pathogen

Hemolysis is a complication in septic infections with Staphylococcus aureus, which utilizes the released Hb as an iron source. S. aureus can acquire heme in vitro from hemoglobin (Hb) by a heme-sequestering mechanism that involves proteins from the S. aureus iron-regulated surface determinant (Isd)...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Sæderup, Kirstine Lindhardt, Stødkilde, Kristian, Graversen, Jonas Heilskov, Dickson, Claire F., Etzerodt, Anders, Hansen, Søren Werner Karlskov, Fago, Angela, Gell, David, Andersen, Christian Brix Folsted, Moestrup, Søren Kragh
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Membrane Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104924/
https://ncbi.nlm.nih.gov/pubmed/27681593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.755934
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi