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The GABA(B) receptor positive modulator BHF177 attenuated anxiety, but not conditioned fear, in rats

GABA(B) (γ-aminobutyric acid B) receptors may be a therapeutic target for anxiety disorders. Here we characterized the effects of the GABA(B) receptor positive allosteric modulator (PAM) BHF177 on conditioned and unconditioned physiological responses to threat in the light-enhanced startle (LES), st...

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Publicat a:Neuropharmacology
Autors principals: Li, Xia, Kaczanowska, Katarzyna, Finn, M. G., Markou, Athina, Risbrough, Victoria B.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537349/
https://ncbi.nlm.nih.gov/pubmed/26002628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.05.001
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