Real-Time PCR Quantification of Heteroplasmy in a Mouse Model with Mitochondrial DNA of C57BL/6 and NZB/BINJ Strains

Mouse models are widely employed to study mitochondrial inheritance, which have implications to several human diseases caused by mutations in the mitochondrial genome (mtDNA). These mouse models take advantage of polymorphisms between the mtDNA of the NZB/BINJ and the mtDNA of common inbred laborato...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Machado, Thiago Simões, Macabelli, Carolina Habermann, Sangalli, Juliano Rodrigues, Rodrigues, Thiago Bittencourt, Smith, Lawrence Charles, Meirelles, Flávio Vieira, Chiaratti, Marcos Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537288/
https://ncbi.nlm.nih.gov/pubmed/26274500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133650
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