Real-Time PCR Quantification of Heteroplasmy in a Mouse Model with Mitochondrial DNA of C57BL/6 and NZB/BINJ Strains

Mouse models are widely employed to study mitochondrial inheritance, which have implications to several human diseases caused by mutations in the mitochondrial genome (mtDNA). These mouse models take advantage of polymorphisms between the mtDNA of the NZB/BINJ and the mtDNA of common inbred laborato...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Machado, Thiago Simões, Macabelli, Carolina Habermann, Sangalli, Juliano Rodrigues, Rodrigues, Thiago Bittencourt, Smith, Lawrence Charles, Meirelles, Flávio Vieira, Chiaratti, Marcos Roberto
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537288/
https://ncbi.nlm.nih.gov/pubmed/26274500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133650
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