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LKB1 Is Required for the Development and Maintenance of Stereocilia in Inner Ear Hair Cells in Mice
The LKB1 gene, which encodes a serine/threonine kinase, was discovered to play crucial roles in cell differentiation, proliferation, and the establishment of cell polarity. In our study, LKB1 conditional knockout mice (Atoh1-LKB1(-/-) mice) were generated to investigate LKB1 function in the inner ea...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4537123/ https://ncbi.nlm.nih.gov/pubmed/26274331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135841 |
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