Absolute quantification of the pretreatment PML-RARA transcript defines the relapse risk in acute promyelocytic leukemia

In this study we performed absolute quantification of the PML-RARA transcript by droplet digital polymerase chain reaction (ddPCR) in 76 newly diagnosed acute promyelocytic leukemia (APL) cases to verify the prognostic impact of the PML-RARA initial molecular burden. ddPCR analysis revealed that the...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Albano, Francesco, Zagaria, Antonella, Anelli, Luisa, Coccaro, Nicoletta, Tota, Giuseppina, Brunetti, Claudia, Minervini, Crescenzio Francesco, Impera, Luciana, Minervini, Angela, Cellamare, Angelo, Orsini, Paola, Cumbo, Cosimo, Casieri, Paola, Specchia, Giorgina
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537013/
https://ncbi.nlm.nih.gov/pubmed/25944686
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