5′RUNX1-3′USP42 chimeric gene in acute myeloid leukemia can occur through an insertion mechanism rather than translocation and may be mediated by genomic segmental duplications

BACKGROUND: The runt-related transcription factor 1 (RUNX1) gene is a transcription factor that acts as a master regulator of hematopoiesis and represents one of the most frequent targets of chromosomal rearrangements in human leukemias. The t(7;21)(p22;q22) rearrangement generating a 5′RUNX1-3′USP4...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zagaria, Antonella, Anelli, Luisa, Coccaro, Nicoletta, Tota, Giuseppina, Casieri, Paola, Cellamare, Angelo, Minervini, Angela, Minervini, Crescenzio Francesco, Brunetti, Claudia, Cumbo, Cosimo, Specchia, Giorgina, Albano, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189616/
https://ncbi.nlm.nih.gov/pubmed/25298786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-014-0066-7
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados