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Increased superoxide leads to decreased flow-induced dilation in resistance arteries of Mn-SOD-deficient mice
The role of mitochondrial manganese-superoxide dismutase (Mn-SOD) in the maintenance of vascular function has not yet been studied. Thus we examined flow- and agonist-induced dilations in isolated mesenteric arteries (~90 µm in diameter) of Mn-SOD heterozygous (Mn-SOD(+/−)) and wild-type (WT) mice....
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| Veröffentlicht in: | Am J Physiol Heart Circ Physiol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536920/ https://ncbi.nlm.nih.gov/pubmed/15637112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01036.2004 |
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